In recent years, the pharmaceutical business has faced unprecedented challenges. The last three years have seen a 24% increase in the average cost of medications in the US due to safety concerns, issues with specific prescriptions, and competition from both non-generic and generic treatments. Prescription costs for those with private insurance decreased by 4% as a result between 2010 and 2013.Similar difficulties face developing nations like Brazil, India, and China. Creating a series of vaccines with therapeutic benefits is one possible answer.In order to treat bacterial illnesses and maintain population and individual health over the long term, antibiotics are required. Antibiotic-resistant bacterial infections, however, pose a threat to world health.